八、常用药物的药代动力学参数参考表
| 药物名称 | 消除速率常数k或β（hr-1） | 半衰期tl/2或tl/2β | 口服吸收（%） | 表现分布容积vb(mg/L) | 有效血浓度范围(mg/L) | 峰时tm(hr) | 蛋白结合率BP(%) | 消除率Cls[L/(hr.kg)] | 解离指数pKa |
| 乙基西梭霉素Nctilmicin | 0.312 | 2.23 | 0.25-0.3 | 4-8 | 0.5-1.0(IM) | 0.78 | |||
| 乙氧萘青霉素Nafillin | 1.39 | 0.5 | 0 | 0.28 | 0.5-1.0(IM) | 90 | 0.39 | 2.6(-COO-) | |
| 乙胺丁醇Ethambutol | 0.198 | 3.5 | 30 | 1.87 | 1-10 | 2-4(PO | 40 | 0.37 | |
| 乙琥胺Ethosuximide | 成人50－60儿童30－50 | 100 | 成人0.62儿童0.69 | 40-100 | 2-4(PO | <2 | 成人0.01-0.013儿童0.016 | 1.3 | |
| 乙酰唑胺Acetazolamide | 0.169 | 4.1
2.4-5.8 |
＞90 | 0.2 | 10-10.5
10-15 |
0.034 | 7.2
9.0 |
||
| 乙酰普鲁卡因胺Acetylprocainamide | 0.082 | 8.5 | 85 | 1.5 | 2-20 | 10 | 0.12 | ||
| 二甲胺四环素Minocycline | 12 | 90 | 0.43 | 0.5-3.0 | 1-3(PO | 75 | 0.025 | ||
| 二性霉素B AmphotericinB | 0.029 | 18-24 | ＜3 | 0.5-1.0 | >90 | 0.025 | |||
| 二氮嗪Diazoxid | 21-36 | 100 | 0.2 | 90-95 | 0.005 | ||||
| 丁胺卡那霉素Amikacin | 0.283-0.311 | 2-3 | 90－100 | 0.25 | 10-25 | 1.0(IM) | 0-20 | 0.069 | |
| 三氯乙醇Trichlorethanol | 4-8 | 0.6 | 0.5(PO | 40 | 0.07 | ||||
| 碘甲腺氯酸钠T3 | 33 | 90－100 | 70-160 | 1-2 | 99.5 | 0.014 | |||
| 万古霉素Vancomycin | 0.12 | 6-8 | 0.47 | 0.2(IV) | 10 | 0.047 | |||
| 土霉素Cxytetracycline | 0.069 | 6-9 | 60－80 | 1.9 | 1.0-10.0 | 1-3(PO) | 20-30 | 0.18 | |
| 双异丙吡胺Dicopyramide | 0.154 | 4.5-7 | 70－100 | 0.8-1.9 | 总药浓度2－5游离药浓度0.5-2 | 0.5-3 | 10-80（与血药浓度有关） | 0.0015-0.004 | 8.34 |
| 双氯青霉素Dicloxacillin | 0.99 | 0.5-0.9 | 0.29 | 15-18 | 1.0(IM) | 96 | 0.29 | ||
| 水合氯醛Choral Hydrate | 4-8 | 0.6 | 10 | 0.5(PO) | 40 | 0.07 | |||
| 心得静Pondolol | 3-4 | 100 | 2.0 | 0.05-0.15 | 1-3 | 0.4 | |||
| 普萘洛尔（心得安）Porpranlolo | 3 | ＞90 | 2.0-4.6 | 0.01-0.2 | 1-1.5(PO) | 90－95 | 0.7 | 9.5 | |
| 心得怡Sotalol | 5-13 | 80－90 | 0.7 | 0.5-4 | 2-3 | 0.054 | 9.8 | ||
| 心得舒Alprenolol | 3 | ＞90 | 3.3 | 0.03-0.1 | 0.5-1.0(PO) | 85 | 0.76 | 9.7 | |
| 对乙酰氨基酚Paracetamol | 2-4 | 85－100 | 0.8-1.0 | 1-10 | 0.5-1.0(PO) | 25 | 0.21 | ||
| 扑米酮Primidone | 成人6－8儿童5－8 | 80－90 | 0.6 | 6-15 | 2-4(PO | 20－30 | 单独用药0.0309合并用药0.0739 | ||
| 去甲丙咪嗪Desipramine | 10－26 | 28－60 | 0.15-0.3 | 2-8(PO | 90 | 1.69 | 10.2 | ||
| 去甲金霉素Demethylchlortetracycline | 0.07-0.043 | 10－16 | 60－80 | 1－2 | 0.5-3 | 1-4(PO | 50 | 0.08 | |
| 去甲替林Nortrpytline | 27 | 60 | 20 | 0.05-0.16 | 4-9(PO) | 92－96 | 0.5 | ||
| 丙咪嗪Imipramine | 8-16 | 80-100 | 20-40 | 0.15-0.5 | 0.5－1.0(PO) | 95 | 1.73 | 9.5 | |
| 丙基硫氧嘧啶Propylthiouracil | 2-4 | 80 | 0.2-0.4 | 1.0(PO) | 75 | 0.07 | 8.3 | ||
| 丙磺舒Probenecid | 6-18 | 100 | 0.12-0.18 | 100-200 | 1-5(PO) | 85-95 | 0.01 | 3.4 | |
| 布洛芬Brufen | 2 | 0.15 | 0.5-1.5(PO) | 99 | 0.052 | ||||
| 左旋多巴Leayodopa | 3 | 20-30（吸收） | 0.5-4 | 8.2 | |||||
| 白霉素Leucomycin | 0.139 | 4.5－5.5 | 2(PO) | 72 | |||||
| 苷珀酸Carbenoxolne | 13－16 | 0.1 | 1-2（空腹PO）饭后(PO) | 0.005 | |||||
| 甲硝唑Metronidazole | 6－14 | 90-100 | 0.6-0.7 | 5-20 | 1-2(PO) | 5-20 | 0.045 | ||
| 可待因Codeine | 0.231 | 2－4 | 50 | 3.45 | 0.025 | 1.0(PO) | 0.8 | 8.2 | |
| 戊巴比妥Pentobarbital | 21－42 | 70-80 | 0.7 | 1-4 | 初次用药6－18长期用药37 | 60-70 | 0.015 | 8.1 | |
| 卡马西平Carbamazepine | 成人10－30儿童8－19 | 90-100 | 0.8-1.4 | 4-12 | 1.0－2.0(IM) | 65-85 | 成人初次用药0.011-0.026儿童初次用药0.028 | ||
| 卡那霉素Kanamycin | 0.289-0.33 | 2-2.5 | 90-95 | 0.25 | 2-8 | 0.5-1.0(IM)1.0(PO) | 0 | 0.077 | 7.2 |
| 头孢氨苄（先锋霉素Ⅳ）Cephalexin | 0.655 | 0.83-1.2 | 90-95 | 0.26 | G(+)
0.5-3G(-)1.0-12 |
15min(IV)0.5-1.0(IM) | 10-15 | 0.18 | 5.3(-COOH-)7.3(-NH2) |
| 头孢匹林（先锋霉素Ⅶ）Cephapirin. | 1.155 | 0.6 | 90-95 | 0.23 | G(+)
0.5-3G(-)1.0-12 |
40-50 | 0.27 | ||
| 头孢娄利定（先锋II）Cephaloridine | 0.62 | 1-1.5 | 90-95 | 0.25 | 同上 | 同上 | 20
10-30 |
0.14 | |
| 头孢噻吩（先锋霉素I）Cephalothin | 1.4 | 0.5-1.0 | 90-95 | 0.25 | 同上 | 同上 | 65
60-80 |
0.23 | |
| 头孢格来星（先锋霉素Ⅲ）Cenhaloglycin | 0.77 | 0.9 | 80-95 | G(+)
0.5-3G(-)1.0-12 |
15min(IV)0.5-1.0IM | 24 | 4.7 | ||
| 头孢唑啉（先锋霉素Ⅴ）Cepahzolin | 0.385 | 1.4-2.2 | 90-95 | 0.15 | 同上 | 5.0-1.0(IM)5min(PO) | 75-85 | 0.058 | 2.3 |
| 头孢雷定（先锋霉素Ⅵ）Cepahzolin | 0.809-0.994 | 40-50min | 90-95 | 0.25 | 同上 | 1.0(PO)5min(IV) | 5-20 | 0.23 | |
| 头孢曲（先锋Ⅶ）Cephacetrile | 0.462 | 1.5 | 90-95 | 0.27 | G(+)
0.5-3G(-)1.0-12 |
1.0(PO)5min(IV) | 22.34 | 0.125 | 1.97 |
| 甲状腺素Thyroxine | 144-168 | 90-95 | 0.1-0.2 | 0.03-0.04 | 99.95 | 0.067 | |||
| 甲氧苄胺嘧定Trimethoprim | 0.07 | 8-12 | 2 | 0.5-12 | 1.5-3.3(PO) | 14 | 0.14 | 7.2 | |
| 甲氧苯青霉素Methicillin | 1.386 | 0.5-1 | 0 | 0.3-0.42 | 1- | 0.5(IM) | 50
35-60 |
0.33 | 2.7 |
| 甲基多巴Methyldopa | 0.35 | 2 | 0.5 | >2 | 4(PO) | 0-20 | 0.17 | 2.2(-COOH)10.6(-NH)12.0(-OH) | |
| 甲基多粘菌素 | 0.154 | 405 | 0.5 | 1－2（IM） | 0.077 | ||||
| 甲烯土霉素Methacycline | 0.0533 | 10-16 | 60-68 | 0.97 | 1.0-10.0 | 1－4(PO)－3(PO) | 70 | 0.052 | |
| 甲苯磺丁脲Tobutamide | 4-8 | 85-100 | 0.1-0.15 | 50-100 | 98 | 0.014 | 5.3 | ||
| 对基水杨酸Para aminosalicylic acid | 0.77 | 0.9 | Sol:100混液：70片:90 | 0.23 | 0.6 | Na:盐0.5-1.0酸型3-4(PO) | 65 | 0.18 | 1.8(-NH)3.6(-COOH) |
| 四环素Tetracycline | 0.099 | 6-10 | 60-80 | 1-2 | 1.0-10.0 | 1-3(PO) | 25-30 | 0.13 | 8.3 |
| 地高辛Digoxin | 0.017 | 30-50 | 50-93 | 6-10 | 0.0006-0.0018 | 1-2(PO)0.5-0.75 | 25 | 0.14 | |
| 西梭霉素Sisomicin | 0.305-0.347 | 2.0-2.5 | 0.25－0.3 | 4-8 | 0.75-1.0(IM) | 0-20 | 0.85 | ||
| 灰黄霉素Griseofulyin | 8-24 | 40-70（微晶型） | 1－2 | 0.3-1.3 | 2-4(PO) | 0.065 | |||
| 华法令Warfarin | 0.016 | 44 15-60 |
100 | 0.1 | 1－10 | 2-8(PO) | 99 | 0.0019 | 4.8 5.0 |
| 优降糖Glybenznyclamide | 5-2 | 0.1 | 2-6(PO) | 99-95 | 0.008 | ||||
| 多粘菌素B PolymyxinB | 0.16 | 3-8 | 0.5－4.0 | 2 (IM) |
<10 | 8.9 | |||
| 多粘菌素E（抗霉素）Polymyxin E | 0.31 | 1.5-8 | 0.5 | 1-2 (IM) |
<10 | 0.07 | 8.9 | ||
| 红霉素Erythromycin | 0.462 | 1.5-3 | 40 | 0.6 | 0.5-3 | 1-4 (PO) |
70-90 | 0.185 | 8.8(-NH2) |
| 吗啡Morphine | 1.5-2.5 | 20 | 1 | 0.07-0.1 | 10-20min (IM) |
35 | 0.35 | 8.0 9.0 |
|
| 庆大霉素Gentamycin | 0.35 | 2 | <5 | 0.25 | 3-8 | 0.5-1 (IM) |
25-30 | 0.087 | |
| 氯,贝丁酯（安妥明）Clofibrate | 8-16 | 90-100 | 0.12 | 80-150 | 96 | 0.007 | |||
| 安定Diazepam | 20-50 | 75-100 | 0.2 | 0.1-1 | 1-2 (PO) |
98 | 0.004 | ||
| 螺内酯（安体舒通）Spironolactone | 10min | 90(吸收) | 0.05 | 3 (PO) |
90 | 0.21 | 3.4 | ||
| 安替比林Antipyrine | 10-15 | 100 | 0.48-0.7 | 10 | 0.033 | ||||
| 异丙肾上腺素Isoprenaline | 2.5 | 0.5 | 80min (PO) 10min(吸入) |
0.14 | 1.4 | ||||
| 异烟肼Isoniazide | 0.193 0.63 |
3.6（慢乙酰化型）0.7-2（快乙酰化型） | 90 | 0.6 | 0.5-1.0 | 1－2 (PO) |
18-30 | 0.12 0.31 |
1.8 3.5 10.8 |
| 抗癫灵Antiepilepsirin | 8-15 | 0.15-0. 4 |
1－4 (PO) |
90 | 0.016 | ||||
| 哌替定Pethidine | 2-4 | 50-70 | 4.7 | 0.2-0.6 | 1－2（IM） | 60 65-75 |
1.09 | 8.7 | |
| 苄二甲胍Bethanidine | 7-15 | 50-100 | 6 | 1－5 (PO) |
8 | 0.38 | |||
| 呋喃妥因Nitrofurantoin | 0.7 | 1.0 | 0.71 | 1-2 | 2 (PO) |
50-60 | 0.49 | 7.2 | |
| 别嘌醇Allopurine | 2-8 | 80 | 2－6 (PO) |
9.0 | |||||
| 利多卡因Lidocaine | 0.46 | 1.5 | 20-50 | 1.6 (0.58-1.19) |
2-5 | 2-5min(IV)0.5(IM) | 60-70 | 0.74 | 7.9 |
| 利福平Rifampicin | 0.25 | 2-5 | 90-95 | 0.6 | 0.5-10 | 1-2 (PO) |
90 | 0.12 | |
| 邻氯青霉素Cloxacillin | 1.39 | 0.5 | 50-80 | 0.15 | 7-14 | 1.0 (IM) |
94 | 0.21 | 2.7 |
| 妥布霉素Tobramycin | 0.251-0.347 | 1.5-3.5 | 90-100 | 0.25 | 2-10 | 1.0 (IM) |
0-20 | 0.07 | |
| 纳洛酮Naloxone | 0.693 | 1 | 20 | 3 | 0.15-1 (IM) |
2.1 | |||
| 阿托品Atropine | 3-4 13-38 |
2-4 10 |
15-50 min (IM) 1.0(PO) |
50 | 0.59 0.27 |
9.9 | |||
| 阿米替林Amitriptyline | 8-20 32-40 |
65 | 8.8 | 0.05-0.3 | 95-98 | 0.44 0.17 |
9.4 | ||
| 乙酰水杨酸（阿司匹林）Acetylsalicylic Acid |
2.0-30(min) | 80-100 | 0.15-0.2 | 20-100（解热镇痛）100-250（抗炎） | 1-2 (PO) |
50-80 | 0.29 | 3.5 | |
| 环磷酰胺Cyclophosphamide | 0.107 | 3-11 | 0.4-0.6 | 1.0 (PO) |
10-20 | 0.05 | |||
| 青霉素Penicillin | 1.386 | 0.5 | 15 (20-40) |
0.25 | 1.5-1.0 | 0.25-0.5 (IM) |
65 | 0.35 | 2.8 |
| 青紫霉素Lividomycin | 0.277-0.372 | 2-2.5 | 1-2 (IM) |
20-30 | |||||
| 苯乙双胍（降糖灵）Phenformin | 0.231 | 3 | 50-70 | 5-10 | 100-240(ng-/ml) | 2-4 (PO) |
20-25 | 1.73 | |
| 苯巴比妥Phenobarbital | 成人53-140儿童37-94 | >90 | 成人0.7儿童0.7-1.2 | 15-40 | 6-18 (PO) |
45-50 | 成人0.0032老人0.0024儿童0.0082新生儿0.0064 | 7.3 | |
| 苯妥英钠Phenytoin | 成人18-30儿童12-22 | 90 | 0.6-0.8 | 10-20 | 4 3-10 (PO) |
88-92 | 0.029 | 803 | |
| 苯海拉明Diphenhydramine | 4-10 | 50 | 3-4 | 0.01-0.1 | 2-4 (PO) |
98-99 | 0.35 | 9.0 7.7 |
|
| 苯唑青霉素Oxacillin | 1.386 | 0.5-1.0 | 70 | 0.25 | 5-6 | 1.0(PO)0.5-1.0 (IM) |
90 | 0.23 | |
| 苯磺唑酮Sulfinpyrazine | 3-5 | 90-100 | 0.15 | 1.0(PO) | 98-99 | 0.026 | |||
| 林可霉素Limcoycin | 0.154 | 4-6 | 40 | 0．35 | 2-10 | 2-4 (PO) 1-2 (IM) |
70 | 0.049 | 7.6(-NH2) |
| 金刚烷胺Amamtadin | 0.315 | 22 | 90－100 | 6 | 1-4 (PO) |
0.19 | |||
| 肼苯达嗪Hydralazine | 2-8 | 80（吸收） | 0.3-0.7 | 0.5-1.5 | 1-4 (PO) |
87 | 0.07 | ||
| 5-氟胞嘧啶5-Flurocytosine | 0.23 | 3-6 | 2-6 (PO) |
48 | |||||
| 氟哌啶醇Haloperidol | 18-30 | 20-30 | 3-6 (PO) |
0.72 | |||||
| 氟氯青霉素Flucloxacillin | 1.39 | 0.50.8 | 45 | 0.12-0.25 | .04 | 96 | 0.2 | ||
| 氢化可的松Hydrocortisone | 0.462 | 0.5-2 | 100 | .03 | 95 | 0.17 | |||
| 茶碱Theophylline | 0．115 | 3－9 | >95 | 0.3-0.6 | 7.5-20 | 1-3 (PO) |
20 | 0.052 | |
| 保泰松Phenylbutazone | 24－120 | 90-100 | 0.1-0.35 | 40-150 | 1-2 (PO) |
90-98 | 0.002 | ||
| 秋水仙碱Colchicine | 0.462 | 0.5－1.5 | 2 | 0.5-2(PO) | 1.39 | ||||
| 呋喃苯胺酸（速尿）Furosemide | 1.4-3.5 | 0-60 | 0.1-0.2 | 0.1-0.2 | 1.0(PO)0.5(IM) | 95-99 | 0.042 | ||
| 奎尼丁Quinidine | 0.096 | 3-16 | 40-90 | 0.5-3.0 | 2-8 | 1-2 (PO) 30-90 min (IM) |
60-80 | 0.13 | |
| 洋地黄毒甙Digitoxin | 0.0058 | 96-168 | 90-100 | 0.5 | 0.01-0.035 | 1-3 (PO) |
95-97 | 0.0026 | |
| 美沙酮Meygadone | 0.091 | 7.6-15 | 100 | 1.5 | 0.48-0.86 | 4 (PO) |
84-87 | 0.09 | |
| 美多心安Metoprolol | 3-4 | 50 | 5.6 | 1.11 | |||||
| 甲氨喋呤Methotrexate | 2-3.5 | 成人0.75-0.8儿童 | 0.2-1.0 (PO) |
1-3 | 50-70 | 4.3 5.5 |
|||
| 氨喋青霉素Ampicillin | 0.6 | 1-1.5 | 50 | 0.4 | 2-8 | 0.5-1.0(IM) | 20 | 0.22 | 2.5(-COOH)7.2(-NH2) |
| 氨酰心胺Atenolol | 6-9 | 50-60 | 0.7 | 0.2-1.3 | 2-4 | 0.065 | |||
| 胺甲苯辛胺Tolamolol | 0.35 | 2.5 | 30 | 3.2 | 2 | 0.89 | |||
| 胍乙啶Guanethidine | 43-120 | 50-80 | 3(OP) | 8.3 11.4 |
|||||
| 胰岛素Insulin | 10min | 0.6 | 10-20μU/ml | 1-10 | 2.5 | ||||
| 吲哚美辛Indomethacin | 2-10 | 9-100 | 0.3-1.6 | 0.5-3 | 1-2 (OP) |
90 | 0.11 | ||
| 莨菪碱Hyoscyamiue | 13-38 | 2-4 | 15-50min(IM)1.0(OP) | 50 | 0.082 | 9.7 | |||
| 唑酮头孢菌素Cephanone | 0.277 | 2.5 | 0.47 | 88 | 0.047 | ||||
| 萘啶酸Nalidixic acid | 0.43 | 1.5-2.0 | 0.26-0.45 | 93 | 0.14 | ||||
| 羧苄青霉素Carbenicillin | 0.462 | 1-1.5 | <10 | 0.18 | 10-150 | 0.5-1.0(IM) | 50 | 0.071 | 2.7(-COOH)2.7-3.9(-NH2) |
| 羟苄四唑头孢菌素Cefamandole | 0.7 | 1.0 | 90-95 | 0.31 | 15min(IV)0.5-1.0(IM) | 75 | 0.22 | ||
| 羟氨苄青霉素Amoxicillin | 0.7 | 1.0-1.5 | 80-90 | 0.47 | 2-8 | 1.0(IM) | 15-20 | 0.26 | 2.4(-COOH)7.4(-NH2) |
| 硫酸奎宁Quinine sulfate | 0.13 | 5.3 | 100 | 2.0 | 2-5 | 1-2(PO) | 70 | 0.26 | 4.1 8.4 |
| 紫霉素Viomycin | 0.35 | 2 | 0.24 | 2(IM) | 0.083 | ||||
| 氯丙嗪 Chiorpromazine |
23-37 | 25 | 20 | 0.5-0.7 | 3-4(PO) 1-2(IM) |
95-98 | 0.46 | 9.3 | |
| 克林霉素Clindamycin | 0.29 | 2-2.5 | 90 | 1.2 | 2-10 | 1.0(PO) 3.0(IM) |
90 | 0.37 | 6.9 7.45 |
| 氯喹Chloroquine | 0.013 | 70-120 | 80-100 | 112 | 6(PO) | 55 | 0.82 | 8.4 | |
| 氯硝基安定Chlornitrazepam | 20-60 | 75-90 | 1.5-4.4 | 1-2(PO) | 45 | 0.052 | 10.8 | ||
| 氯霉素Chloramphenicol | 0.277 | 1.5-4 | 75-90 | 成人0.55-0.98儿童1.1-2.5 | 4-20 | 2-3 (PO) |
60-80 | 0.15 | 5.5 |
| 氯磺丙脲Chlorpropamide | 36-40 | 0.1-0.2 | 30-140 | 1-2(PO) | 5-10 | 0.0027 | 5.0 | ||
| 普鲁卡因胺Procainamide | 2.5-4.5 | 75-95 | 1.7-2.2 | 4-8 | 1.0-2(PO)30min(IM) | 15 | 0.4 | 9.2 | |
| 卡巴咪嗪Carbamazepine(Tegretol) | 20-60 | 0.8-1.4 | 2-10 | 8 (PO) |
65-83 | 0.036 | |||
| 催产素Oxytccin | 5-16min | 0.2 | 4-120(pg/ml) | 30 | 0.83 | ||||
| 叠氮霉素Azidocillin | 0.866 | 0.6-1.0 | 0.35-0.6 | 83-85 | 0.43 | 2.8 | |||
| 美西律（慢心律）Mexiletine | 0.06 | 11.5 | ≈100 | 4.5 | 0.5-20 | 0.27 | |||
| 新霉素Neomycin | 0.35 | 2 | 0.25 | 1.0(IM) | 0.087 | ||||
| 溴苄胺Bretylium | 0.07 | 10 | 0.2-0.4 | ||||||
| 脱氧土霉素Doxycycline | 0.03 | 14-25 | 90 | 1-2 | 1-10 | 1-3 (PO) |
25-31 | 0.52 | 3.4 |
| 沷尼松Prednisone | 0.693 | 1 | 0.5-0.6 | 1.0 (PO) |
54 | 0.38 | |||
| 沷尼松龙Prednisolone | 0.217 | 3 | 0.5-0.6 | 1.0 (PO) |
54 | 0.13 | |||
| 碳酸锂Lithum carbonate | 0.028 | 25 | >95 | 0.7 | 0.4-0.7mmol/L | 1-2 (PO) |
0.02 | 6.8 | |
| 链霉素Streptomycin | 0.277 | 2-3 | 0.25 | 0.5-3(IM) | 30-35 | 0.07 | |||
| 镇痛新Pentazocine | 0.375 | 1.85 | 3 | 0.03-0.1 | 1-3 (PO) 15-60 min (IM) |
60-70 | 1.12 | 11.2 | |
| 磺胺Sulfanamide | 0.077 | 9 | 80-85 | 100-150 | 2-4 (PO) |
5-20 | 10.4 | ||
| 磺胺二甲胺基嘧啶(SM2)Sulfamethoxazole | 0.099 | 7 | 0.61 | 80-100 | 2-4 (PO) |
80 | 0.06 | 7.4 | |
| 磺胺甲基异噁唑(SMZ)Sulfamethoxazole | 0.063 | 8-12 | 85-100 | 0.3 | 90-100 | 2-4 (PO) |
68 | 0.021 | 6 |
| 磺胺异噁唑(SIZ)Sulfamethoxazole | 0.12 | 16 | 85-100 | 0.15 | 80-150 | 2-4 (PO) |
68 | 0.017 | 6 |
| 磺胺嘧啶 (SD) Sulfaisoxazole |
0.041 | 17 | 85-100 | 0.6 | 2-4 (PO) |
68 | 0.025 | 6.3 | |
| 噻吩甲氧头孢菌素Cefoxitin | 0.99 | 0.7 | 90-95 | 0.29 | 0.005-0.01 | 同上 | 45 | 0.29 | |
| 噻吗心安Timolol | 2-4 | 72 | 1.8 | 1-2 | 73 | 0.42 | |||
| 噻嗪类利尿药Thiazide | 1-4 | 60-90 | 1-3 (PO) |
99 |